ONOPORDUM ANATOLICUM TOHUMLARININ ANTIOKSİDAN AKTİVİTELERİ
Öz
Onopordum cinsi Türkiye’de ondokuz takson ile temsil edilmekte ve Anadolu’da tıbbi amaçla geleneksel olarak kullanılmaktadır. O. anatolicum tohumlarının etil alkol ve su özütlerinin antioksidan özellikleri β-karoten/linoleik asit, DPPH serbest radikal süpürme, indirgeme gücü, ve metal şelatma testlerini içeren farklı kimyasal testlerle araştırıldı. Ayrıca, özütlerin toplam fenolik ve flavonoid içerkikleri de belirlendi. Genel olarak, etil alkol özütü yüksek toplam fenolik içerikle önemli antioksidan aktivite (metal şelatlama dışında) sergilemiştir. Bununla birlikte, su özütü çalışılan örnekler arasında en güçlü şelatlama aktivitesine sahiptir. Bu çalışma O. anatolicum özütlerinin doğal antioksidanların yeni bir kaynağı olarak gıda ve farmakoloji endüstrisinde kullanılabileceğini önermektedir.
Referanslar
Altundag, E., & Ozturk, M. (2011). Ethnomedicinal studies on the plant resources of east Anatolia, Turkey. Procedia-Social and Behavioral Sciences, 19, 756-777.
Aruoma, O.I., 1996. Assessment of potential prooxidant and antioxidant actions, Journal of the American Oil Chemists Society, 73(12), 1617-1625.
Arvouet-Grand, A, Vennat, B, Pourrat, A, Legret, P (1994). Standardisation d’un extrait de propolis et identification des principaux constituants. Journal De Pharmacie De Belgique 49, 462–468.
Chavan, J. J., Gaikwad, N. B., Kshirsagar, P. R., & Dixit, G. B. (2013). Total phenolics, flavonoids and antioxidant properties of three Ceropegia species from Western Ghats of India. South African Journal of Botany, 88, 273-277.
Dapkevicius, A, Venskutonis, R, Van Beek, TA, Linssen, PH (1998). Antioxidant activity of extracts obtained by different isolation procedures from some aromatic herbs grown in Lithuania. Journal of the Science of Food and Agriculture 77, 140-146.
Davis PH, Mill RR, Tan K (eds) (1988). Flora of Turkey and the east Aegean Islands (Suppl. 1.), Vol. 10. Edinburgh: Edinburgh University Press.
Deliorman‐Orhan, D., Şenol, S., Kartal, M., & Orhan, I. (2009). Assessment of antiradical potential of Calluna vulgaris (L.) Hull and its major flavonoid. Journal of the Science of Food and Agriculture, 89(5), 809-814.
Dinis, TCP, Madeira, VMC, Almeida, LM (1994). Action of phenolic derivates (acetoaminophen, salycilate and 5-aminosalycilate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Archives of Biochemistry and Biophysics 315, 161–169.
Fridovich, I., 1995. Superoxide radical and superoxide dismutases. Annual Review of Biochemistry, 64, 97–112.
Halliwell, B., 1994. Free radicals, antioxidants, and human disease: curiosity, cause, or consequence. Lancet, 344, 721– 724.
Halliwell, B., 2007. Dietary polyphenols: Good, bad or indifferent for your health? Cardiovascular Research, 73, 341-347.
Halliwell, B., Gutteridge J.M.C. 1999. Free radicals in Biology and Medicine, 3 rd ed., Oxford University Press, New York, USA, pp10-121.
Hatano, T, Edamatsu, R, Mori, A, Fujita, Y, Yasuhara, E (1989). Effect of interaction of tannins with co-existing substances. vı. effects of tannins and related polyphenols on superoxide anion radical and on DPPH radical. Chemical and Pharmaceutical Bulletin 37, 2016–2021.
Hatipoğlu, G., Sökmen, M., Bektaş, E., Daferera, D., Sökmen, A., Demir, E., & Şahin, H. (2013). Automated and standard extraction of antioxidant phenolic compounds of Hyssopus officinalis L. ssp. angustifolius. Industrial Crops and Products, 43, 427-433.
Hou, W.C., Lin, R.D., Cheng, K.T., Hung, Y.T., Cho, C.H., Chen, C.H., Hwang, S.Y., Lee, M.H., 2003. Free radical scavenging activity of Taiwanese native plants. Phytomedicine 10, 170–175.
Ito, N., Hirose, M., Fukushima, S., Tsuda, H., Shirai, T., Tatematsu, M. 1986. Studies on antioxidants: Their carcinogenic and modifying effects on chemical carcinogenesis. Food and Chemical Toxicology, 24, 1071-1082.
Jeong, C. H., Choi, G. N., Kim, J. H., Kwak, J. H., Kim, D. O., Kim, Y. J., & Heo, H. J. (2010). Antioxidant activities from the aerial parts of Platycodon grandiflorum. Food chemistry, 118(2), 278-282.
Larson, R.A., 1988. The antioxidants of higher plants, Phytochemistry, 27, 969-972.
Mükemre, M., Behçet, L., & Çakılcıoğlu, U. (2015). Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey). Journal of ethnopharmacology, 166, 361-374.
Oke, F., & Aslim, B. (2010). Biological potentials and cytotoxicity of various extracts from endemic Origanum minutiflorum O. Schwarz & PH Davis. Food and Chemical Toxicology, 48(6), 1728-1733.
Özüdoğru, B., Akaydın, G., Erik, S., & Yesilada, E. (2011). Inferences from an ethnobotanical field expedition in the selected locations of Sivas and Yozgat provinces (Turkey). Journal of ethnopharmacology, 137(1), 85-98.
Polat, R., Cakilcioglu, U., & Satıl, F. (2013). Traditional uses of medicinal plants in Solhan (Bingöl—Turkey). Journal of ethnopharmacology, 148(3), 951-963.
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996). Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free radical biology and medicine, 20(7), 933-956.
Rios, A.D.O., Antunes L.M., Bianchi M.D.L.P., 2009. Bixin and lycopene modulation of free radical generation induced by cisplatin-DNA interaction, Food Chemistry, 113, 1113-1118.
Safer, A.M., Hepatotoxicity induced by the antioxidant food additive butylated hydroxytoluene (BHT), in rats: An electron microscopical study, Histology and Histopathology, 14, 391-406, (1999).
Singleton, VL, Orthofer, R, Lamuela-Raventŏs, RM (1999). Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods in Enzymology 299, 152-178.
Susanna A, Garcia-Jacas N (2007). Tribe Cardueae Cass. In: Kadereit JW, Jeffrey C, editors. The Families and Genera of Vascular Plants, Vol. 8. Berlin: Springer-Verlag, pp. 123–146.
Terpinc, P., Čeh, B., Ulrih, N. P., & Abramovič, H. (2012). Studies of the correlation between antioxidant properties and the total phenolic content of different oil cake extracts. Industrial Crops and Products, 39, 210-217.
Wang, T., Jonsdottir, R., & Ólafsdóttir, G. (2009). Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds. Food Chemistry, 116(1), 240-248.
Zengin, G., & Aktumsek, A. (2014). Investigation of antioxidant potentials of solvent extracts from different anatomical parts of Asphodeline anatolica E. Tuzlaci: an endemic plant to Turkey. African Journal of Traditional, Complementary and Alternative Medicines, 11(2), 481-488.
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